Meeting Banner
Abstract #1305

Automatic Segmentation and Analysis of Carotid and Middle Cerebral Artery Using 3D CUBE MRI with IMSDE Blood Suppression

Chengcheng Zhu1, Andrew J. Patterson1, Jin Zhu2, Martin John Graves1, Jonathan H. Gillard1

1University Department of Radiology, University of Cambridge, Cambridge, Cambridgeshire, United Kingdom; 2Department of Computer Science, Peking University, Beijing, China

Atherosclerotic plaques presenting within extra- and intra-cranial arteries are known to be risk factors for subsequent stroke. High resolution artery vessel wall MRI can visualize high-risk morphologic factors of plaques in vivo and help patient risk stratification. 3D CUBE has demonstrated a high SNR efficiency as well as intrinsic black-blood effects in vessel wall imaging. Improved motion-sensitized driven-equilibrium (iMSDE) preparation provides better blood suppression than traditional spatial saturation and double inversion-recovery (DIR) methods. This study investigated the automatic segmentation and analysis of carotid and middle cerebral artery (MCA) using T1w/T2w CUBE combined with iMSDE blood suppression.