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Abstract #1317

A Multimodality Cross-Validation Study of Cardiac Perfusion Using MR and CT

Giorgos Papanastasiou1, 2, Lucy Kershaw1, Michelle Williams2, Mark Dweck2, Shirjel Alam2, Saeed Mirsadraee1, Calum Gray1, Tom MacGillivray1, David C. Newby1, 2, Scott I. Semple1, 2

1Clinical Research Imaging Center, University of Edinburgh, Edinburgh, United Kingdom; 2Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom

Modern advances in magnetic resonance (MR) and computed tomography (CT) perfusion imaging techniques have developed methods for myocardial perfusion assessment. However, individual imaging techniques present limitations that are possible to be surpassed by a multimodality cross-validation of perfusion imaging and analysis. We calculated the absolute myocardial blood flow (MBF) in MR using a Fermi function and the transmural perfusion ratio (TPR) in CT perfusion data in a patient with coronary artery disease (CAD). Comparison of MBF and TPR results showed good correlation emphasizing a promising potential to continue our multimodality perfusion assessment in a cohort of patients with CAD.