Abstract #1340

Retrospectively Triggered Local PWV Measurements in the Murine Aorta Using a Radial Sampling

Patrick Winter¹, Eberhard Rommel¹, Wolfgang Rudolf Bauer², Peter M. Jakob¹,³, Volker Herold¹

¹Dept. of Experimental Physics 5, University of Wrzburg, Wrzburg, Bavaria, Germany; ²Medizinische Klinik und Poliklinik I, Universittsklinikum Wrzburg, Wrzburg, Germany; ³Magnetic Resonance Bavaria, Wrzburg, Bavaria, Germany

In this work, we introduce a retrospectively triggered PC-FLASH sequence with a radial sampling for a robust measurement of the local pulse-wave-velocity (PWV) in the murine abdominal aorta. The sequence was tested on a 17.6T small animal system on mice. A Navigator signal was extracted from the k-space center and used for the retrospective reconstruction of movie frames of the aortic motion. The PWV was determined using the QA-method. The results were compared with a prospectively triggered radial PWV measurement using a pneumatic measurement of the thoracic motion as trigger signal. The PWV value obtained with the retrospective measurement