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Abstract #1370

Optimization and Standardization of TI-Selection in Contrast Enhanced Viability Imaging by Automated Analysis of Rapid Quantitative T1 Mapping

Andreas Greiser1, Andr Rudolph2, Matthias Alexander Dieringer2, Julius Traber2, Evelyn Polzin2, Edgar Mueller1, Jeanette Schulz-Menger2

1Healthcare Sector, Siemens AG, Erlangen, Bavaria, Germany; 2Working Group Cardiac MR, Charit, ECRC Humboldt-University, Berlin and HELIOS Clinics, Berlin, Germany

Suboptimal TI selection in late gadolinium enhancement (LGE) cardiac MRI can be overcome by a new robust, user-independent approach to TI optimization based on a fast T1-mapping protocol and automated segmentation. The T1 mapping allows a shorter breath-hold than the standard TI scout protocol. The T1-map-based TI times are in good agreement with the user-selected TI-scout-based values (266.440.5ms vs. 266.935.4 ms) but vary from the TI scout values (251.635.7 ms). T1-map-derived TI times match the user-defined values better than the objective TI scout values. The presented method provides a new option for standardization in clinical research and routine CMR.