James William Goldfarb1, 2, Usama Hasan1, Wenguo Zhao1, Jing Han1
1Department of Research and Education, Saint Francis Hospital, Roslyn, NY, United States; 2Program in Biomedical Engineering, SUNY Stony Brook, Stony Brook, NY, United States
In patients with myocardial infarction, high-pass filtered (HPF) phase imaging was compared with quantitative resting myocardial perfusion and late gadolinium-enhanced (LGE) infarct imaging. Infarct to remote segmental upslope percent showed a similar reduction in resting perfusion with the presence of microvascular obstruction (MVO) and myocardial hemorrhage at all stages of myocardial infarction. Reduced segmental resting perfusion was a sensitive, but not specific indicator of MVO and intramyocardial hemorrhage. Susceptibly-weighted HPF-phase imaging represents a new quantitative, high quality method for the detection of myocardial hemorrhage and is associated with reduced resting perfusion and MVO.