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Abstract #1475

Hyperpolarized 83Kr Imaging on a Clinical 3 T System

Daniel James Lee1, Joseph Six2, Matthew Clemence3, Paul M. Glover1, Thomas Meersmann2, Karl Stupic2, 4

1SPMMRC, University of Nottingham, Nottingham, Nottinghamshire, United Kingdom; 2Medical School, University of Nottingham, Nottingham, Nottinghamshire, United Kingdom; 3Philips Healthcare, Guildford, Surrey, United Kingdom; 4National Institute of Standards and Technology, Boulder, CO, United States


Imaging of hyperpolarized 83Kr has been achieved on a clinically available 3T system. The isotope 83Kr has the potential to become a new contrast agent for respiratory MRI where changes such as inflammation, lung surfactant concentration, and alveolar shape could be monitored as important pathologies for lung disease. The presence of 83Kr was confirmed spectroscopically and images of a phantom are presented.