Abstract #1492

3D Radial Oxygen Enhanced Imaging in Normal and Asthmatic Human Subjects

Stanley Kruger¹, Kevin M. Johnson,¹², Scott K. Nagle,¹², Robert Cadman¹, Laura C. Bell³, Nizar Jarjour⁴, Sean B. Fain¹,²

¹Medical Physics, University of Wisconsin, Madison, WI, United States; ²Radiology, University of Wisconsin, Madison, WI, United States; ³Medical Physics, University of Wisconsin-Madison, Madison, WI, United States; ⁴School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States

3D radial UTE SPGR is a new technique in oxygen enhanced MRI that combines oversampling the center of k-space as well as short TE to yield a 3D isotropic volume of oxygen enhanced signal that is robust against cardiac motion artifact and T2* decay, while providing full lung coverage. Mean Signal Enhancement (MSE) values corresponding to regional pulmonary ventilation in humans are compared across normal and asthmatic human subjects.