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Abstract #1492

3D Radial Oxygen Enhanced Imaging in Normal and Asthmatic Human Subjects

Stanley Kruger1, Kevin M. Johnson, 12, Scott K. Nagle, 12, Robert Cadman1, Laura C. Bell3, Nizar Jarjour4, Sean B. Fain1, 2

1Medical Physics, University of Wisconsin, Madison, WI, United States; 2Radiology, University of Wisconsin, Madison, WI, United States; 3Medical Physics, University of Wisconsin-Madison, Madison, WI, United States; 4School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States


3D radial UTE SPGR is a new technique in oxygen enhanced MRI that combines oversampling the center of k-space as well as short TE to yield a 3D isotropic volume of oxygen enhanced signal that is robust against cardiac motion artifact and T2* decay, while providing full lung coverage. Mean Signal Enhancement (MSE) values corresponding to regional pulmonary ventilation in humans are compared across normal and asthmatic human subjects.