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Abstract #1497

Oxygen-Enhanced T1-Mapping of the Lung: Reproducibility and Impact of Different Gas Delivery Methods

Julius Renne1, Jan Hinrichs1, Christian Schnfeld1, Marcel Gutberlet1, Peter M. Jakob2, Frank Wacker1, Jens Vogel-Claussen1

1Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Lower Saxony, Germany; 2Experimental Physics (Biophysics), University of Wrzburg, Wrzburg, Germany

Oxygen-enhanced MRI of the lung is a promising tool for the development of early disease markers or long-term monitoring of disease activity. However, so far few data exist about the reliability of this method in a clinical setting. Healthy individuals were scanned two times using two different gas delivery methods usually available in clinical settings. A full covering face mask with a half-closed gas delivery system showed highly reproducible T1 values and oxygen transfer function. Furthermore, using this mask lower variability between healthy individuals was seen compared to a loose-fit mask.