Chun-Tsun Shih1,
Yi-Ru Lin1, Chih-Ping Liao1, Bo-Rong Huang1,
Shang-Yueh Tsai2, 3
1Department
of Electronic and Computer Engineering, National Taiwan University of Science
and Technology, Taipei, Taiwan; 2Graduate Institute of Applied
Physics, National Chengchi University, Taipei, Taiwan; 3Research
Center for Mind, Brain and Learning, National Chengchi University, Taipei,
Taiwan
Proton echo planar spectroscopic imaging (PEPSI) has been shown to be able to acquire liver fat content in single breath hold. To further extend spatial resolution or to decrease breath hold period, Generalized Autocalibrating Partially Parallel Acquisitions (GRAPPA) was enrolled to accelerate PEPSI acquisition. GRAPPA weighting coefficients were estimated from fully phase encoded data from individual coil element using Auto-Calibration Signal (ACS) lines. After GRAPPA reconstruction, lipid contents were quantified using LCModel and compared to full-sampled PEPSI. In conclusion, 2-fold acceleration using GRAPPA with ACS lines is feasible to reduce scan time in both 16x32 and 32x32 PEPSI data.