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Abstract #1544

Impact of Volume-Of-Interest Limited Registration to DCE-MRI of Human Kidney

Frank G. Zllner1, Marcel Reich1, Lothar R. Schad1

1Computer Assisted Clinical Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Baden-Wrttemberg, Germany

Dynamic contrast enhanced imaging of the kidneys using magnetic resonance imaging (DCE-MRI) is a non-invasive method for determining the renal function.Major problems for quantitative analysis are motion artifacts due to breathing of the patient preventing a valid determination of the parameters. The kidneys move mainly in head-feet direction, however sometimes not synchronous. we compared a volume-of-interest (VOI) limited registration approach to a registration of the whole volumes. The presented VOI-limited registration could reduce coronal motion in the data sets on average by 50%.