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Abstract #1582

Measurement of Tissue Extracellular Volume in Health and Amyloidosis Using Equilibrium Contrast MRI

Steve Bandula1, Sanjay Banypersad2, Daniel Sado2, Stuart Taylor1, Shonit Punwani1, James Moon2

1Centre for Medical Imaging, University College London, London, United Kingdom; 2The Heart Hospital, University College London Hospital , London, United Kingdom

Equilibrium MRI (EQ-MRI) is a new technique that can quantify extracellular volume fraction and has been used to measure diffuse myocardial fibrosis. In this study, EQ-MRI is utilized to define the extracellular volume within healthy abdominal organs and demonstrate a significant increase in tissue ECV in patients with amyloidosis a disease defined by extracellular deposition of abnormal proteins.