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Abstract #1666

MRI Visualization of Local Drug Delivery

Morgan Giers1, Qingwei Liu2, Ken Schmidt3, Gregory H. Turner2, Alex McLaren3, Michael Caplan4, Ryan Mclemore3

1School of biological and health Systems Engineering, Arizona State University, Tempe, AZ, United States; 2Neuroimaging Research, Barrow Neurological Institute, Phoenix, AZ, United States; 3Orthopaedic Residency, Banner Good Samaritan Medical Center, Phoenix, AZ, United States; 4Harrington Bioengineering Department, Arizona State University, Tempe, AZ, United States

In this study, we have developed an imaging-based technique, using a gadolinium-marked small molecule, for monitoring the distribution of locally delivered antimicrobial from bone cement in extremity wounds that will enable real time analysis of drug concentration and adjustment of clinical management.