Abstract #1672

Quantitative T2* Mapping of in vivo Human Meniscus Using 2D Duel Echo Radial Sequence with Minimal Phase Excitation Pulse at 3 T

Ping-Huei Tsai¹,², Teng-Yi Huang³, Hsiao-Wen Chung⁴, Fong Y. Tsai², Wing P. Chan¹

¹Department of Radiology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan; ²Imaging Research Center, Taipei Medical University, Taipei, Taiwan; ³Department of Electrical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan; ⁴Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan

Previous studies have emphasized that the meniscis complex alignment of collagen fibers contributes to the execution of this function. The purpose of this study is to design a 2D multi-slice dual echo radial sequence with a minimal phase excitation pulse for facilitating visualization of the fiber orientation in human meniscus based on quantitative T2* mapping. Our findings demonstrate that the proposed method allows enhanced visualization of structural details of the human meniscus, and which contributes to derive the spatial T2* distribution and fiber orientation for diagnosing early degenerative changes.