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Abstract #1764

Evaluating MRI T1rho Contrast in Hepatic Cell Carcinoma: Initial Study

Jiayu Sun1, Rui Xia1, Fabao Gao1, Jie Zheng2, Bing Wu1

1Department of Radiology, West China Hospital,Sichuan University, Chengdu, Sichuan, China; 2Mallinckrodt Institute of Radiology,Washington University School of Medicine in St. Louis, St.Louis, MO, United States

6 patients with hepatic cell carcinoma confirmed on liver biopsy were scanned on a Siemens Trio 3.0 T whole body scanner. A novel B0- and B1-insensitive multi-contrast T1rho imaging with segmented trueFISP readout was performed on the slice of the central tumor during end-inspiratory breath holding,Correlation between mean T1 and pathological grading was excellent in all cases for liver tumors.The longer T1rho ratio in tumor tissue may add additional dimension for staging tumors and treatment monitoring.