Abstract #1784

High-Resolution Variable Density Spiral Diffusion Weighted Sequence for Prostate and Bladder Wall

Hui Zhang¹, Huijun Chen¹, Wenchuan Wu¹, Xiaoying Wang², Feiyu Li², Chun Yuan¹,³, Hua Guo¹

¹Center for Biomedical Imaging Research & Department of Biomedical Engineering, Tsinghua University, Beijing, China; ²Departement of Medical Imaging, Peking University First Hospital, Beijing, China; ³Department of Radiology, University of Washington, Seattle, WA, United States

Single-shot EPI diffusion weighted imaging, as a traditional method for assessment of disease aggressiveness in clinical application, is burdened by severe distortion as well as low resolution and SNR. In this study, we introduced the interleaved variable density spiral diffusion weighted imaging (VDS-DWI) into the prostate application first time and compares with traditional clinical EPI DWI with different b values and higher resolution. We found that it can provide images with well-reserved structure details and higher SNR and resolution and considerable scan time even in high b value. Our findings indicate that VDS-DWI might be a desirable technique to improve the anatomy structures retention and resolution with considerable SNR and time in clinical prostate and urinary bladder wall detection.