Eveliina Lammentausta1,
Gamzegul M. Behrouz2, Elli-Noora Salo3, Ville-Veikko
Telkki2, Susanna Ahola2, Jessica M. Rosenholm4,
Roberto Blanco Sequeiros1, 5, Miika T. Nieminen3,
5
1Department
of diagnostic Radiology, Oulu University Hospital, OYS, Oulu, Finland; 2Department
of Physics, University of Oulu, Oulu, Finland; 3Department of
diagnostic Radiology, Oulu University Hospital, OYS, Finland, Finland; 4Center
for Functional Materials, Laboratory of Physical Chemistry, Department of
Natural Sciences, bo Akademi University, Turku, Finland; 5Department
of Radiology, University of Oulu, Oulu, Finland
Novel amorphous manganese oxide (MnOx) nanostructures were examined in various concentrations from 0.01 mM t0 1 mM at four different field strengths (3T, 4.7T, 7.1T and 9.4T) to determine its T1 relaxivity. MnOx displayed substantially higher relaxivities than typical clinically used gadolinium based contrast agents and thus is a very promising candidate for stem cell labeling and dynamic imaging studies.
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