Abstract #1902

Using Ellipsoidal Microshells to Generate Multispectral Contrast

Gary Zabow¹,², Stephen Dodd¹, Alan P. Koretsky¹

¹NINDS, National Institutes of Health, Bethesda, MD, United States; ²Electromagnetics Division, National Institute of Standards & Technology, Boulder, CO, United States

A new class of microengineered multispectral contrast agent is introduced based on ellipsoidal microshell structures. In principle, the new ellipsoidal geometries allow for higher spectral resolution than previously demonstrated microfabricated multispectral agents, improving detection sensitivity and agent multiplexing potential. This talk discusses the theory behind these new agents, considers ways to fabricate the required microstructure geometries, and presents initial NMR data from the first sets of such agents.