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Abstract #1924

Earths Field MRI Using Continuous SABRE Hyperpolarization

Niels Schwaderlapp1, Thomas Lickert1, Sebastien Baer1, Jrgen Hennig2, Dominik v. Elverfeldt1, Jan-Bernd Hvener1

1Department of Radiology, Medical Physics, University Hospital Freiburg, Freiburg, Germany; 2Department of Radiology, Medical Physics, University Medical Center Freiburg, Freiburg, Germany

The method of hyperpolarization of signal amplification by reversible exchange (SABRE) is used to acquire images in the earths field. The polarization field of an EFMRI system is applied prior to each measurement and utilized here to continuously hyperpolarize a liquid sample. This allows the observation of a substance hyperpolarized by SABRE for long term (>10 min) and thereby allows imaging with a simple spin echo sequence without the need of moving the sample. This technique can be used to promote EFMRI of hyperpolarized targeted molecules.