Abstract #1969

in vivo Investigation of Choline Compounds with 1H and 31P MRS in the Patients with Liver Disorders.

Martin Gajdosik¹, Ladislav Valkovic¹, Marek Chmelik¹, Stefan Traussnigg², Michael Trauner², Siegfried Trattnig¹, Martin Krssk,¹³

¹MR Centre of Excellence, Department of Radiology, Medical University of Vienna, Vienna, Austria; ²Gastroenterology & Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria; ³Endocrinology & Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria

The measurements of choline containing compounds in the liver lack the clean conclusion. In this study the link between 1H & 31P MR spectroscopy (MRS) regarding to choline containing compound and hepatic lipids in patients with liver disorders - non-alcoholic fatty liver disease and steatohepatitis was examined. The MRS measurements allowed to resolve the resonances of choline containing metabolites and we could find certain links between proton and phosphorus MRS derived measures of hepatic metabolism status.