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Abstract #1997

Measurement of Transverse Relaxation Times in Brain Tumors

Akshay Madan1, Sandeep Ganji1, Elizabeth A. Maher2, Changho Choi3

1Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States; 2Harold C. Simmons Cancer Center, UT Southwestern Medical Center, Dallas, TX, United States; 3Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, United States


In this study we performed invivo T2 measurement of metabolites like N-acetylaspartate, Creatine, Choline and water in glioma patients for comparison with normal brain using single voxel point resolved spectroscopy at multiple echo times at 3T. We calculated T2 using monoexponential nonlinear fitting of metabolite signal estimates obtained from LCModel.