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Abstract #2021

Group-Mean Template Modelling of NAA- And NAAG-Edited MR Spectra

Nicolaas A. J. Puts1, 2, Mona M. Mohamed1, Peter B. Barker1, 2, Richard Anthony Edward Edden1, 2

1The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, United States; 2FM Kirby Centre for functional neuroimaging, Kennedy Krieger Institute, Baltimore, MD, United States

NAA and NAAG can be seperated in vivo using edited MRS. Our previous study used rough methods to analyse spectra, and the creation of basis sets is problematic. Here we shows that a template-based fitting model based on the group-mean of the data is suitable for fitting NAA and NAAG.