Abstract #2058

Axon Diameter Distribution (ADD) MRI

Raisa Z. Freidlin¹, Evren Ozarslan², Sinisa Pajevic¹, Michal E. Komlosh³, Peter J. Basser³

¹NIH/CIT/DCB, Bethesda, MD, United States; ²Radiology, BWH, Harvard Medical School, Boston, MA, United States; ³NIH/NICHD/PPITS, Bethesda, MD, United States

Obtained the axon diameter distribution (ADD) for fascicles in any orientation, anywhere within a brain volume, is based on estimate of an average propagator in each voxel using a 3-D generalization that determines the direction of maximum diffusivity and then estimates the DW signal attenuation profile.