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Abstract #2101

SPatio-Temporal ENcoded Diffusion-Weighted Breast MRI Studies

Eddy Solomon1, Noam Nissan1, 2, Hadassa Degani3, Lucio Frydman1

1Chemical Physics, Weizmann Institute of Science, Rehovot, Israel; 2Biological Regulation, Weizmann Institute of Science, Rehovot, Israel; 3Biological Regulation, Weizmann Institue of Science, Rehovot, Israel

Breast imaging is particularly challenging owing to a number of factors, including the relatively high fat/water heterogeneities that characterize breast, the off-center character of the targeted organs, and the unavoidability of breathing/cardiac motions. Here we exploit SPEN’s abilities to deliver quality single-scan images even from challenging regions subject to all these problems, to explore its use in DW MRI. Diffusion SPEN measurements were carried out at 3T in female breast analyses, showing significant advantages in anatomical and diffusional information vis- -vis EPI.