Meeting Banner
Abstract #2109

Distinct Cerebral Tissue Alterations in Diabetic and Hereditary Neuropathic Pain as Revealed by Voxel-Based Morphometry and Tract-Based Spatial Statistics

Arzu Ceylan Has1, Aslihan Taskiran Sag2, Cagri Mesut Temucin3, Nese Oztekin2, Fikri Ak2, Kader Karli Oguz4

1National Magnetic Resonance Research Centre (UMRAM), Bilkent University, ANKARA, Turkey; 2Department of neurology, Ankara Numune Education and Research Hospital, ANKARA, Turkey; 3Department of Neurology, Faculty of Medicine, and Institute of Neurological Sciences and Psychiatry, Hacettepe University, ANKARA, Turkey; 4Department of Radiology and National Magnetic Resonance Research Centre (UMRAM), Hacettepe University and Bilkent University, ANKARA, Turkey

Neuropathic pain is caused by a lesion or a disease of the somatosensory system itself. Its usually more prominent in acquired pathologies of nerve fibers like diabetic neuropathy (DNP) despite less severe degeneration than hereditary neuropathies (HNP). On the basis of differences in etiopathogenetic mechanisms, we hypothesized that grey and white matter alterations would reveal distinct patterns in patients with DNP and HNP.