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Abstract #2111

Laterality of the Corticospinal Tract and Variation with Handedness: The Findings of a DTI Study

Khin Khin Tha1, Satoshi Terae2, Hiroyuki Hamaguchi2, Kinya Ishizaka2, Makoto Hirotani2, Kazuyuki Minowa3, Yuriko Suzuki4, Hiroki Shirato1

1Department of Radiobiology and Medical Engineering, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan; 2Hokkaido University Hospital, Sapporo, Hokkaido, Japan; 3Hokkaido University Graduate School of Dental Medicine, Sapporo, Hokkaido, Japan; 4Philips electronics Japan, Ltd., Tokyo, Japan

Laterality in the DTI indices of the corticospinal tract (CST) of the brain and the spinal cord and their variation with handedness were evaluated in 8 left handers and 8 age- and gender-matched right handers. The DTI indices were compared across the two sides and between the two handers, at various CST levels. The results revealed a similar pattern of asymmetry in the indices between the brain and the spinal cord for both handers. The values differed between the two handers. The knowledge of laterality of the DTI indices and variation with handedness is important in interpretation of the indices.