Abstract #2119

Test-Retest Reliability in Fibre Orientation Distribution (FOD) Measurements in HARDI Data

Kai-kai Shen¹, Stephen Rose¹, Jurgen Fripp¹, Katie McMachon², Greig de Zubicaray³, Nicholas Martin⁴, Paul Thompson⁵, Margret Wright⁴, Olivier Salvado¹

¹Australian eHealth Research Centre, CSIRO, Herston, Queensland, Australia; ²Centre for Advanced Imaging, University of Queensland, Brisbane, Queensland, Australia; ³School of Psychology, University of Queensland, Brisbane, Queensland, Australia; ⁴Queensland Institute of Medical Research, Brisbane, Queensland, Australia; ⁵Imaging Genetics Center, Laboratory of Neuro Imaging, UCLA, Los Angeles, CA, United States

We evaluated the test-retest reliability for measures based on the fibre orientation distribution (FOD) using constrained spherical deconvolution (CSD). We derived measurements in the peak direction identified from the FOD, and evaluated the test-retest reliability for these FOD peak amplitudes using the intra-class correlation (ICC) coefficient. We visualized the ICC coefficients on the FOD orientation plot. We compared the reliability of measuring the FOD peak amplitudes and the fractional anisotropy (FA) derived from the diffusion tensor imaging (DTI) model.