Abstract #2123

Improved Angular Resolution with GQI2: A New Diffusion Imaging Q-Space Cartesian Lattice Reconstruction Method

Ian Nimmo-Smith¹, Frank Fang-Cheng Yeh², Eleftherios Garyfallidis³

¹MRC Cognition and Brain Sciences Unit, Cambridge, Cambridgeshire, United Kingdom; ²Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, United States; ³University of Cambridge, Cambridge, Cambridgeshire, United Kingdom

GQI2 is a new non-parametric method for reconstruction of diffusion imaging data acquired with Q-space cartesian lattice design. Using simulations and human data we show it has superior ability to resolve angular directions in voxels with two or three crossing fiber directions. GQI2 also has efficiency advantages over diffusion spectrum imaging (DSI) in terms of computer memory and computation time.