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Abstract #2145

Comparing 3D Velocity-Selective Arterial Spin Labeling to 3D Pseudocontinuous Arterial Spin Labeling

Zungho Zun1, Ajit Shankaranarayanan2, Greg Zaharchuk1

1Radiology, Stanford University, Stanford, CA, United States; 2GE Healthcare, Menlo Park, CA, United States

Velocity-selective arterial spin labeling (VSASL) is a promising method for measuring cerebral blood flow (CBF) in patients with slow or delayed flow. Most previous works on VSASL were demonstrated using 2D imaging, and no previous work reported comparison of VSASL and PCASL, both with 3D imaging and with the same quantification method. In this study, VSASL was combined with 3D image acquisition and was performed in normal volunteers along with 3D PCASL. CBF maps acquired using two methods showed consistent results. Measured signal-to-noise ratio (SNR) from VSASL was about 30% lower than that of PCASL, but was adequate to provide good image quality.