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Abstract #2158

Accelerating Arterial Spin Labeled Perfusion Imaging Using Compressed Sensing

Yihang Zhou1, 2, Jie Zheng3, Dong Liang4, Leslie Ying1, 2

1Electrical Engineering, University at Buffalo, Buffalo, NY, United States; 2Department of Biomedical Engineering, University at Buffalo, Buffalo, NY, United States; 3Department of Radiology, Washington University, St. Louis, MO, United States; 4Paul C. Lauterbur Research Centre for Biomedical Imaging, Shenzhen, China

Arterial spin labeled (ASL) MRI method has been used as an alternative to first-pass perfusion imaging in assessing end organ perfusion. It has the advantage of avoiding administration of any contrast agent. However, this method is sensitive to motion artifacts due to prolonged data acquisition time for each T1 weighted image. The motion artifacts will greatly degrade the image quality and reduce the accuracy of perfusion measurements. In this study, the feasibility of accelerating ASL acquisition using compressed sensing is investigated. Results on calf muscle and cardiac experiments demonstrate compressed sensing is able to preserve the perfusion information with accelerated acquisition.