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Abstract #2240

Stability of Resting-State Brain Activity Fluctuations Across Time: Evidence from fMRI and MEG

Om Bhatt1, Jed Meltzer1, Bernhard Ross1, J. Jean Chen1

1Rotman Research Institute, Baycrest, University of Toronto, Toronto, ON, Canada

Magnetoencephalography (MEG) is potentially valuable in clarifying the physiological mechanisms of resting-state fMRI-based functional connectivity. However, MEG and fMRI experiments cannot be performed simultaneously on the same subject. In this work, we present evidence for a stability of intrinsic brain activity across time. This stability is higher in certain brain regions, and higher during eyes-open than in eyes-closed resting state. These findings will enhance our ability to capitalize on the spatially resolved neuro-electric information from MEG to inform resting-state fMRI interpretations of brain activity. Future work will address the link between these spectral features and connectivity.