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Abstract #2347

Cross-Field Analysis of the Accuracy of Hypercapnia Calibrated BOLD

Nicholas P. Blockley1, Valerie E M Griffeth2, Peter Jezzard1, Daniel P. Bulte1

1FMRIB, University of Oxford, Oxford, United Kingdom; 2Center for Functional MRI, University of California San Diego, La Jolla, CA, United States

The calibrated BOLD technique was originally optimised for 1.5T, and was later revised for 3T. However, with the arrival of 7T systems it is unclear what the optimal implementation should be and how this will affect accuracy. In this study we extended an existing detailed model of the BOLD signal to simulate the BOLD response at these field strengths. This model was used to examine the error in oxygen metabolism measurements across fields and provide a guide to the expected BOLD scaling factor M at 7T.