Olen Rambow1, John D. Hazle1, John Clark2, Jingfei Ma1
1Imaging Physics Department, University of Texas MD Anderson Cancer Center, Houston, TX, United States; 2Department of Electrical Engineering, Rice University, Houston, TX, United States
The possible solutions to the signal equations in two-point Dixon imaging are the intersection points of two ellipses in the water-fat plane. When the multi-peak spectrum of fat is included in the signal model, the ellipses tilt in such a way that at certain echo time combinations only one solution remains in the region where water and fat are both non-negative. This makes it possible to select the correct solution without phase correction. Simulation, phantom, and in vivo data show that the accuracy achievable by this method depends on both SNR and the echo times.