Abstract #2430

3D Multifrequency Abdominal MR Elastography Using a Piezoelectric Driver, Single-Shot Wave-Field Acquisition, and Multifrequency Dual Parameter Inversion

Jing Guo¹, Sebastian Hirsch², Rolf Reiter¹, Thomas Kroencke¹, Patrick Asbach³, Juergen Braun⁴, Ingolf Sack¹

¹Department of Radiology, Charite - University Medicine Berlin, Berlin, Germany; ²Department of Radiology, Charit - Universittsmedizin Berlin, Berlin, Germany; ³MVZ CBF Radiologie, Charite - University Medicine Berlin, Berlin, Germany; ⁴Department of Medical Informatics, Charite - University Medicine Berlin, Berlin, Germany

3D multifrequency MRE including nonmagnetic shear wave excitation and least-squares multifrequency inversion is introduced for improving the spatial resolution in abdominal-MRE viscoelasticity maps. The new method is demonstrated in health volunteers and patients with ascites and portal hypertension. All three technical key-points, driver, single-shot wave field acquisition and dual parameter inversion, are new in their application to abdominal MRE and contribute to an improved clinical protocol for the precise and spatially highly resolved mechanical assessment of the liver and the spleen.