Ria Mazumder1, Bradley Dean Clymer1, Richard White2, 3, Arunark Kolipaka2, 3
1Department of Electrical and Computer Engineering, The Ohio State University, Columbus, OH, United States; 2Deparment of Radiology, The Ohio State University, Columbus, OH, United States; 3Deptarment of Internal Medicine, Division of Cardiology, The Ohio State University, Columbus, OH, United States
Formalin fixed hearts have been actively used in research to study mechanical properties such as stiffness of left ventricular (LV) myocardium. However, the stiffness of the fresh hearts greatly differs from that of the formalin fixed hearts. Mechanical testing has been the gold standard to determine the stiffness of the myocardium. In this study MR Elastography is used to compare the stiffness of LV myocardium between fresh and formalin fixed hearts within the same animal specimen. We have observed that formalin fixed hearts are significantly stiffer than the fresh hearts.