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Abstract #2463

Correction of B1 and Estimation of Oversampling Effect to Enable Accurate T1 Mapping Using 3D Variable Flip Angle Technique

Kosuke Morita1, 2, Tomoyuki Okuaki3, Masanori Komi1, Akiko Kuraoka4, Daisuke Utsunomiya2, Mika Kitajima2, Masahiro Hashida1, Yasuyuki Yamashita2

1Radiology, Kumamoto University Hospital, Kumamoto, Japan; 2Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University Hospital, Kumamoto, Japan; 3Philips Electronics Japan, 13-37, Kohnan 2-chome, tokyo, Japan; 4Radiology, Kumamoto University Hospital , Kumamoto, Japan

The purpose of our study was to acquire precise 3D T1maps by variable flip angle DESPOT1 method with B1 correction for clinical MR imaging. Moreover, the T1 value of outer-slice regions on 3D acquisition using the ordinary slice selective RF pulse with imperfect rectangular shape is not accurate. To resolve this problem, we evaluated the effect of the B1 inhomogeneity and slice-oversampling factor on 3D T1maps using a phantom and volunteers. Our experiments showed that the T1 value was improved by B1 correction using variable flip angle method and T1 value for 3D T1mapping was improved by optimizing slice-oversampling factor.