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Abstract #2498

Feasibility of in-vivo Quantitative Susceptibility Mapping (QSM) in the Kidneys

Huan Tan1, Jon Thacker2, Tian Liu3, Yi Wang3, Pottumarthi Vara Prasad4, 5

1NorthShore University HealthSystem, Evanston , IL, United States; 2Northwestern University, Evanston, IL, United States; 3Weill Cornell Medical College, New York, NY, United States; 4NorthShore University HealthSystem, Evanston, IL, United States; 5The University of Chicago Pritzker School of Medicine, Chicago, IL, United States

The magnetic susceptibility of tissue can be measured using quantitative susceptibility mapping (QSM), a novel MRI technique that utilizes a 3D multi-echo gradient echo sequence for data acquisition. Since the quantification of susceptibility is inherently based on the phase information and necessitates 3D acquisition, respiratory motion remains a key challenge. In this study, we implemented a prospective cross-pair navigator method to minimize motion effects. The technique was tested in five volunteers, and the preliminary analysis supports feasibility of acquiring QSM in vivo in human kidneys.