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Abstract #2521

Imaging Chick Embryos with SPIO Nanoparticles Using SWIFT

Luning Wang1, Yangqing Lu2, Khan Hekmatyar3, Steve Stice2, Qun Zhao1

1Department of Physics and Astronomy, University of Georgia, Athens, GA, United States; 2Department of Animal and Dairy Science, University of Georgia, Athens, GA, United States; 3BioImaging Research Center (BIRC), University of Georgia, Athens, GA, United States


Magnetic resonance imaging (MRI) has been used for studying the dynamics of chick embryo development and growth. This can be repeated observations on the same embryo on a longitudinal basis, using high resolution ultra-high-field (7 Tesla or higher) MR scanners. MRI-based cell tracking using super-paramagnetic iron oxide (SPIO) particles provide an excellent means of cell monitoring in in-vivo. In this work, a novel sweep imaging with Fourier transformation (SWIFT) sequence, compared with conventional fast spin echo (FSE) and gradient-recalled echo (GRE) sequences, will be used to scan a chick embryo injected with SPIO nanoparticles.

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