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Abstract #2531

Effect of Saturation Pulse Duration and Strength on Parallel Transmission Based Amide Proton Transfer MRI of the Prostate

Guang Jia1, Saba N. Elias1, Ronney Abaza2, Debra L. Zynger3, Zarine K. Shah1, Lai Wei4, Robert R. Bahnson2, Michael V. Knopp1

1Department of Radiology, The Ohio State University, Columbus, OH, United States; 2Department of Urology, The Ohio State University, Columbus, OH, United States; 3Department of Pathology, The Ohio State University, Columbus, OH, United States; 4Center for Biostatistics, The Ohio State University, Columbus, OH, United States


This study shows the importance of APT-MRI contrast optimization based on pulse duration and power strength in clinical prostate cancer patient examinations and its benefits to further develop this methodology into an imaging biomarker.