Abstract #2531

Effect of Saturation Pulse Duration and Strength on Parallel Transmission Based Amide Proton Transfer MRI of the Prostate

Guang Jia¹, Saba N. Elias¹, Ronney Abaza², Debra L. Zynger³, Zarine K. Shah¹, Lai Wei⁴, Robert R. Bahnson², Michael V. Knopp¹

¹Department of Radiology, The Ohio State University, Columbus, OH, United States; ²Department of Urology, The Ohio State University, Columbus, OH, United States; ³Department of Pathology, The Ohio State University, Columbus, OH, United States; ⁴Center for Biostatistics, The Ohio State University, Columbus, OH, United States

This study shows the importance of APT-MRI contrast optimization based on pulse duration and power strength in clinical prostate cancer patient examinations and its benefits to further develop this methodology into an imaging biomarker.