Garrett W. Astary1,
Marcus K. Peprah2, Charles R. Fisher3, Paul R. Carney4,
Malisa Sarntinoranont5, Mark W. Meisel2, Michele V.
Manuel3, Thomas H. Mareci1
1Biochemistry
and Molecular Biology, University of Florida, Gainesville, FL, United States;
2Physics, University of Florida, Gainesville, FL, United States; 3Materials
Science and Engineering, University of Florida, Gainesville, FL, United
States; 4Biomedical Engineering, University of Florida,
Gainesville, FL, United States; 5Mechanical and Aerospace
Engineering, University of Florida, Gainesville, FL, United States
Our goal is to develop an alloy that is magnetic susceptibility-matched to brain tissue to create electrodes and cannula that do not distort MR images. We have developed an MR method for measuring magnetic susceptibility and evaluated the method by measuring the susceptibility of copper-tin alloys and comparing the results to SQUID magnetometry. The MR method was evaluated at 4.7 T and 11.1 T and deviated by less than 3.1% from SQUID magnetometry measurements. The MR method is free of geometric and sample-size restrictions associated with SQUID magnetometry and can be implemented at any facility with MR hardware.
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