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Abstract #2585

Comparison of DTI Data in 5-Year Old Children Acquired Using Standard and Navigated DTI Sequences

A. Alhamud1, B. Laughton2, Khader M. Hasan3, Andr J. W. van der Kouwe4, Ernesta M. Meintjes1

1Human Biology, MRC/UCT Medical Imaging Research Unit, University of Cape Town, Cape Town, Western Cape, South Africa; 2 Paediatrics and Child Health, Stellenbosch University and Tygerberg Hospital, Cape Town, Western Cape, South Africa; 3University of Texas Health Science Center at Houston, Houston, TX, United States; 4Department of Radiology, Massachusetts General Hospital, Charlestown, MA, United States


Many diffusion tensor imaging (DTI) studies have reported changes in DTI measures especially fractional anisotropy (FA) when studying brain development or neuro-pathological diseases. Moreover, other studies have found that motion and retrospective motion correction may introduce a positive or negative bias to DTI data.