A Novel Double Tuned 4T 1H/17O Head Volume Coil

Jing-Huei Lee¹, Mathew Norris¹, Elizabeth M. Fugate¹, Nikolai I. Avdievich², Hoby P. Hetherington²

The development and implementation of the CMRO₂ imaging approach based on high-field ¹⁷O magnetic resonance spectroscopic (MRS) imaging, combined with brief inhalation of ¹⁷O-isotope-enriched oxygen gas, has received increased interest. However, the low sensitivity of ¹⁷O MR signal has limited the potential of this technique. In this work, we introduced a novel double tuned ¹H/¹⁷O head volume coil, in which the ¹H coil is driven in quadrature mode and the ¹⁷O coil utilizes phased array approach.