Dominik Berthel1, Michael Neumaier2, Titus Lanz1, Thomas Kaulisch2, Detlef Stiller2
1Rapid Biomedical GmbH, Rimpar, Germany; 2In-Vivo Imaging Unit, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany
Positioning the muscle fibers along the main magnetic field (B0) is important to obtain well-resolved and undistorted lipid MR-spectra. For qualified 1H-MR spectroscopy (1HMRS) of intra-myocellular lipids (IMCL) we present a positioning and fixation setup for the mouse calf combined with an optimized and highly sensitive two channel RF receive coil. By the use of this setup fast positioning of the in vivo objects are assured, incorrect voxel-positions will be avoided and so a high throughput of IMCL-studies can be achieved.