Abstract #2845

Differential Diffusivity in Parkinsonism

Mohit Saxena¹, S. Senthil Kumaran², Madhuri Behari¹, Vinay Goyal¹

¹Department of Neurology, All India Institute of Medical Sciences, New Delhi, Delhi, India; ²Department of NMR, All India Institute of Medical Sciences, New Delhi, Delhi, India

Parkinsons Disease presents difficulty in coordinated movements due to loss of dopaminergic neurons in the substantia nigra. We observed a significant loss in the whole brain fibers in PD subjects as compared to in controls. We observed significantly low FA values in the SMA and thalamus.