Ashok Panigrahy1,
2, Jessica L. Wisnowski1, 3, Rafael C. Ceschin4,
Stefan Bluml2
1Pediatric
Radiology, Childrens Hospital of Pittsburgh, Pittsburgh, PA, United States; 2Childrens
Hospital Los Angeles, Los Angeles, CA, United States; 3Brain and Creativity
Institute, University of Southern California, Los Angeles, CA, United States;
4Children's Hospital of Pittsburgh, Pittsburgh, PA, United States
We used MRS to examine cerebral metabolism in the parietal white matter of a large cohort of high-risk preterm infants in relation to two MRI defined patterns of white matter injury and present the first evidence of altered NAA/MI ratio, T2 relaxation, and thalamic volume, in association with punctate white lesions, but not diffuse extensive high signal intensity (DESHI)
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