Meeting Banner
Abstract #2991

Measurement of Hemodynamic Parameters in Carotid Occlusive Disease Using Partial Volume Corrected PCASL fMRI

Iris Asllani1, Shazia Dharssi1, Marykay Pavol1, Ronald L. Lazar1, Randolph S. Marshall1

1Columbia University, New York, NY, United States

There is converging evidence that cerebral hemodynamic failure affects cognitive function in carotid artery disease, but inconsistent methods of measuring both the behavioral and the hemodynamic state have hindered this line of inquiry from influencing clinical management. Here, we present preliminary data from patients with 100% carotid stenosis on whom we measured hemodynamic parameters such as baseline and activation CBF as well as arterial transit times (ATT) using PCASL fMRI.