Pseudocontinuous Arterial Spin Labeling with Prospective Motion Correction (PCASL-PROMO)

Zungho Zun¹, Ajit Shankaranarayanan², Greg Zaharchuk¹

Arterial spin labeling (ASL) scans can benefit from motion correction techniques particularly for disoriented or uncooperative patients. Prospective motion correction (PROMO) is a rigid-body motion correction method based on image domain using 3-plane navigator. In this work, PROMO was incorporated into pseudocontinuous ASL (PCASL) sequences for cerebral blood flow (CBF) measurements. In the presence of brain motion, blurring artifacts were generated in ASL images, but these were removed dramatically using PROMO. In addition, ASL imaging was not perturbed by navigator imaging in PROMO and the labeling efficiency was not affected by the brain motion.