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Abstract #3033

Improving ASL Using 3D bSSFP with Background Suppression and Two-Dimensional GRAPPA

Hua-Shan Liu1, Daeun Kim1, Randall B. Stafford1, Se-Hong Oh1, Sung-Hong Park2, Danny J.J. Wang3, Ze Wang1, Misung Han4, John A. Detre1, Jongho Lee1

1University of Pennsylvania, Philadelphia, PA, United States; 2Korean Advanced Institute for Science and Technology, Daejun, Korea; 3University of California, Los Angeles, LA, United States; 4University of California, San Francisco, San Francisco, CA, United States


In this study, we investigated the characteristics of a 3D bSSFP sequence in ASL. We developed a BS-pCASL bSSFP with 2D (Ky and Kz) GRAPPA acceleration. The results were compared with conventional 2D EPI ASL. We demonstrated the advantages of a 3D BS pCASL-bSSFP sequence with high quality data while keeping the acquisition fast and efficient.