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Abstract #3035

Feasibilty of Dual-Echo PCASL and PASL BOLD-RCBF fMRI in Olfactory Experiments

Ana Beatriz Solana1, Elena Molina2, Pablo Garca-Polo2, Juan Antonio Hernndez-Tamames2, 3, Susana Borromeo2, Fernando Zelaya4, Francisco del Pozo1

1Universidad Politcnica de Madrid, Pozuelo de Alarcn, Madrid, Spain; 2Universidad Rey Juan Carlos, Mstoles, Madrid, Spain; 3Fundacin CIEN-Fundacin Reina Sofa. Madrid, Madrid, Spain; 4King's College London, London, United Kingdom

The study of the primary olfactory cortex with fMRI is difficult because of its location in medial temporal lobe, highly affected by magnetic field inhomogeneities causing both local image distortion and signal dropout. Arterial Spin Labelling is a promising fMRI technique, , above all in these distorted areas, due to its shorter TE and also because its a quantitative measurement. However, ASL-fMRI is challenging due to its low SNR. In this work, we showed the feasibility and advantages of using simultaneous dual-echo BOLD-ASL fMRI acquisition with spiral readout using PCASL and PASL in olfactory experiments in healthy volunteers.