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Abstract #3045

Effect of NMDA-Receptor Inhibition on Relative Cerebral Blood Flow to the Hippocampus and Medial Prefrontal Cortex: A Placebo Controlled Repeated Measures Study of Ketamine in Healthy Young Men

Najmeh Khalili Mahani1, Marieke Niesters1, Matthias J.P. van Osch2, Albert Dahan1

1Anesthesiology, Leiden University Medical Center, Leiden, Netherlands; 2Radiology, Leiden University Medical Center, Leiden, Netherlands

Pseudocontinuous ASL (pCASL) reveals regional effects of ketamine on relative cerebral blood flow in the hippocampus, basal ganglia, cerebellum and medial visual and prefrontal cortical regions.