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Abstract #3049

Perfusion Imaging of Renal Tumors at 3 Tesla Using Pulsed Continuous Arterial Spin Labeling

Ananth J. Madhuranthakam1, Ivan E. Dimitrov2, David C. Alsop3, Ivan Pedrosa1

1Radiology and Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States; 2Philips Healthcare, Cleveland, OH, United States; 3Radiology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States

We investigated pulsed continuous arterial spin labeling combined with background suppression for renal perfusion imaging at 3 Tesla using single shot fast spin echo acquisition. High image quality was achieved in normal volunteers and five patients with renal tumors. Averaged across all subjects, mean perfusion was measured as 23572 mL/100g/min in cortex and 13425 mL/100g/min in medulla and in agreement with values previously reported in the literature. Perfusion was heterogeneous in tumors and varied considerably across patients, most likely depending upon the tumor histopathologic subtypes.